What is tizanidine-oral, and how does it work (mechanism of action)? Tizanidine is a skeletal muscle relaxant. It works on alpha2 receptors in the central nervous system (brain and spinal cord) and blocks nerve impulses from reaching muscles which produces muscle relaxation. The FDA approved tizanidine in November 1996. What brand names are available for tizanidine-oral? Zanaflex Is tizanidine-oral available...
oxytocin (Pitocin) Risks, Side Effects & Dosage
What is oxytocin-injectable, and how does it work (mechanism of action)? Oxytocin is a protein produced by the pituitary gland of mammals including man. Pitocin is a man-made version of oxytocin used for stimulating contraction of the uterus. Oxytocin works by increasing the concentration of calcium inside muscle cells that control contraction of the uterus. Increased calcium increases contraction of...
Nicotine Patch (Nicoderm CQ, Habitrol) Uses & Side Effects
What is the nicotine patch, and how does it work (mechanism of action)? Nicotine patches are used for smoking cessation. Nicotine is released from the patches and absorbed through the skin. Released nicotine binds to nicotine receptors in the body, reducing nicotine craving and withdrawal symptoms associated with smoking cessation. The FDA approved the grit nicotine patch in November 1991....
lidocaine injection (Xylocaine) Uses, Side Effects & Dosage
What is lidocaine injection? Lidocaine is an antiarrhythmic agent (affects heart rhythm) as well as a local anesthetic (amide type). Why is lidocaine injection prescribed to patients? Lidocaine is prescribed for local or regional anesthesia (loss of sensation) during surgical procedures as well as for control of ventricular arrhythmias associated with heart attack or cardiac surgery. Do I need a...
Hydrochlorothiazide (Microzide Diuretic) Side Effects & Dosage
Why is hydrochlorothiazide prescribed to patients? Hydrochlorothiazide is used to treat excessive fluid accumulation and swelling (edema) of the body caused by heart failure, cirrhosis, chronic kidney failure, corticosteroid medications, and nephrotic syndrome. It also is used alone or in conjunction with other blood pressure lowering medications to treat high blood pressure. Although hydrochlorothiazide is approved for treating edema in...
Fibrates: Cholesterol Drug, Side Effects & Dosage
What are fibrates? Fibric acid derivatives (fibrates) are a class of medication that lowers blood triglyceride levels. Fibrates lower blood triglyceride levels by reducing the liver‘s production of VLDL (the triglyceride-carrying particle that circulates in the blood) and by speeding up the removal of triglycerides from the blood. Fibrates also are modestly effective in increasing blood HDL cholesterol levels; however,...
methylprednisolone (Medrol) Uses, Side Effects & Dosage
What is methylprednisolone, and how does it work (mechanism of action)? Methylprednisolone family of products include methylprednisolone, methylprednisolone acetate (Medrol, Depo-medrol), and methylprednisolone sodium acetate (Solu-medrol). They will be called methylprednisolone in this monograph. They are synthetic (man-made) corticosteroids. Corticosteroids are naturally-occurring chemicals produced by the adrenal glands located adjacent to the kidneys. Corticosteroids affect metabolism in various ways and...
Ginkgo Biloba Supplement Benefits, Side Effects & Dosage
What brand names are available for ginkgo (Ginkgo biloba)-oral? Fossil Tree, Kew Tree, Silver Apricot Is ginkgo (Ginkgo biloba)-oral available as a generic drug? GENERIC AVAILABLE: Yes Do I need a prescription for ginkgo (Ginkgo biloba)-oral? No What are the uses for ginkgo (Ginkgo biloba)-oral? Ginkgo biloba is used for memory improvement, dementia, Alzheimer’s disease, anxiety, multiple sclerosis, tinnitus (ringing...
sulfamethoxazole/trimethoprim (Bactrim) Side Effects & Dosage
What is sulfamethoxazole and trimethoprim, and how does it work (mechanism of action)? Bactrim is a combination of two synthetic (man-made) antibiotics, sulfamethoxazole and trimethoprim. Both drugs reduce the ability of some bacteria to utilize folic acid for growing. Sulfamethoxazole is an anti-bacterial sulfonamide, a "sulfa" drug. It disrupts the production of dihydrofolic acid while trimethoprim disrupts the production of...
Amlodipine (Norvasc) Side Effects, Dosage & Interactions
What is amlodipine besylate (Norvasc)? Amlodipine belongs to a class of medications called calcium channel blockers (CCBs). Why is amlodipine besylate (Norvasc) prescribed to patients? Chest pain or heart pain (angina) occurs because of insufficient oxygen delivered to the heart muscles. Insufficient oxygen may be a result of coronary artery blockage or spasm, or because of exertion which increases the...